Article
The influence of the renin gene on alcohol consumption in Dahl rats.
Alcoholism, clinical and experimental research - 1 Feb 1991
O'Dowd B F, Grupp L A
Abstract excerpt
A rat renin allele (the S-allele) has been identified in Dahl rats which cosegregates with increases in blood pressure. Rats with a double dose of the allele--the salt-sensitive hypertensive rats--have low renin activity compared with the salt-resistant hypertensive rat that does not have this S-allele. Alcohol consumption in rats has also been shown to vary with renin activity, and the possible involvement of...
Topics
- Alcohol Drinking
- Alleles
- Animals
- Hypertension
- Introns
- Mutagenesis, Insertional
- Phenotype
- Rats
- Rats, Inbred Strains
- Renin
- Renin-Angiotensin System