Article
A Hardy-Weinberg equilibrium test for analyzing population genetic surveys with complex sample designs.
American journal of epidemiology - 15 Apr 2010
Moonesinghe Ramal, Yesupriya Ajay, Chang Man-Huei, Dowling Nicole F, Khoury Muin J, Scott Alastair J
Abstract excerpt
Testing for deviations from Hardy-Weinberg equilibrium is a widely recommended practice for population-based genetic association studies. However, current methods for this test assume a simple random sample and may not be appropriate for sample surveys with complex survey designs. In this paper,...
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