Article
Association study of four key folliculogenesis genes in polycystic ovary syndrome.
BJOG : an international journal of obstetrics and gynaecology - 1 May 2010
Sproul K, Jones M R, Mathur R, Azziz R, Goodarzi M O
Abstract excerpt
Polycystic ovaries and impaired fertility are the result of abnormal folliculogenesis. Our objective was to determine the role of four candidate folliculogenesis genes in the development of polycystic ovary syndrome (PCOS). Women with and without PCOS (335 cases; 198 controls) were genotyped for single nucleotide polymorphisms in GDF9, BMP15, AMH, and AMHR2. Variants in these genes were not associated with PCOS....
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