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Article

Cancer-derived mutations in the fibronectin III repeats of PTPRT/PTPrho inhibit cell-cell aggregation.

Cell communication & adhesion - 1 Dec 2009

Zhang Peng, Becka Scott, Craig Sonya E L, Lodowski David T, Brady-Kalnay Susann M, Wang Zhenghe

Abstract excerpt

Abstract The receptor protein tyrosine phosphatase T PTPrho is the most frequently mutated tyrosine phosphatase in human cancer. PTPrho mediates homophilic cell-cell aggregation. In its extracellular region, PTPrho has cell adhesion molecule-like motifs, including a MAM domain, an immunoglobulin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor-Like Protein Tyrosine Phosphatases, Class 2

Source

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Identifiers

PMID: 20230342
DOI: 10.3109/15419061003653771
PMCID: PMC2921943

Genes

PTPRT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20230342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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