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Article

Site-specific and dose-dependent effects of glucocorticoid receptor phosphorylation in yeast Saccharomyces cerevisiae.

Steroids - 1 Jun 2010

Popovic Natasa, Ruzdijic Sabera, Kanazir Dusan T, Niciforovic Ana, Adzic Miroslav, Paraskevopoulou Elissavet, Pantelidou Constantia, Radojcic Marija, Demonacos Constantinos, Krstic-Demonacos Marija

Abstract excerpt

The glucocorticoid receptor (GR) signal transduction and transcriptional regulation are efficiently recapitulated when GR is expressed in Saccharomyces cerevisiae. In this report we demonstrate that the in vivo GR phosphorylation pattern, hormone dependency and interdependency of phosphorylation events were similar in yeast and mammalian cells. GR phosphorylation at S246 exhibited inhibitory effect on S224 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20223255
DOI: 10.1016/j.steroids.2010.03.001
PMCID: PMC2880793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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