Article
Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function.
Immunogenetics - 1 Apr 2010
Pan Feng, Yang Tie-Lin, Chen Xiang-Ding, Chen Yuan, Gao Ge, Liu Yao-Zhong, Pei Yu-Fang, Sha Bao-Yong, Jiang Yan, Xu Chao, Recker Robert R, Deng Hong-Wen
Abstract excerpt
As pivotal immune guardians, B cells were found to be directly associated with the onset and development of many smoking-induced diseases. However, the in vivo molecular response of B cells underlying the female cigarette smoking remains unknown. Using the genome-wide Affymetrix HG-133A GeneChip microarray, we firstly compared the gene expression profiles of peripheral circulating B cells between 39 smoking and...
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