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Article

Genome-wide scan identifies variant in TNFSF13 associated with serum IgM in a healthy Chinese male population.

PloS one - 1 Jan 2012

Yang Ming, Wu Yongming, Lu Yanmei, Liu Changyuan, Sun Jielin, Liao Ming, Qin Min, Mo Linjian, Gao Yong, Lu Zheng, Wu Chunlei, Zhang Youjie, Zhang Haiying, Qin Xue, Hu Yanling, Zhang Shijun, Li Jianling, Dong Min, Zheng S Lilly, Xu Jianfeng, Yang Xiaobo, Tan Aihua, Mo Zengnan

Abstract excerpt

IgM provides a first line of defense during microbial infections. Serum IgM levels are detected routinely in clinical practice. And IgM is a genetically complex trait. We conducted a two-stage genome-wide association study (GWAS) to identify genetic variants affecting serum IgM levels in a Chinese population of 3495, including 1999 unrelated subjects in the first stage and 1496 independent individuals in the...

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Identifiers

PMID: 23118916
DOI: 10.1371/journal.pone.0047990
PMCID: PMC3485370

Genes

TNFSF13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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