Article
Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele.
Tissue antigens - 1 Jul 2006
Kennedy L J, Quarmby S, Happ G M, Barnes A, Ramsey I K, Dixon R M, Catchpole B, Rusbridge C, Graham P A, Hillbertz N S, Roethel C, Dodds W J, Carmichael N G, Ollier W E R
Abstract excerpt
Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.