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Article

Identifying cellular pathways modulated by Drosophila palmitoyl-protein thioesterase 1 function.

Neurobiology of disease - 1 Oct 2010

Saja Stephanie, Buff Haley, Smith Alexis C, Williams Tiffany S, Korey Christopher A

Abstract excerpt

Infantile-onset Neuronal Ceroid Lipofuscinosis (INCL) is a severe pediatric neurodegenerative disorder produced by mutations in the gene encoding palmitoyl-protein thioesterase 1 (Ppt1). This enzyme is responsible for the removal of a palmitate post-translational modification from an unknown set of substrate proteins. To better understand the function of Ppt1 in neurons, we performed an unbiased dominant...

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Identifiers

PMID: 20206262
DOI: 10.1016/j.nbd.2010.02.010
PMCID: PMC2914843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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