Article
Rapid differentiation of Francisella species and subspecies by fluorescent in situ hybridization targeting the 23S rRNA.
BMC microbiology - 8 Mar 2010
Splettstoesser Wolf D, Seibold Erik, Zeman Ella, Trebesius Karlheinz, Podbielski Andreas
Abstract excerpt
BACKGROUND: Francisella (F.) tularensis is the causative agent of tularemia. Due to its low infectious dose, ease of dissemination and high case fatality rate, F. tularensis was the subject in diverse biological weapons programs and is among the top six agents with high potential if misused in bioterrorism. Microbiological diagnosis is cumbersome and time-consuming. Methods for the direct detection of the...
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