Article
How to avoid phenotypic misclassification in using joint destruction as an outcome measure for rheumatoid arthritis?
Rheumatology (Oxford, England) - 1 Aug 2010
van der Helm-van Mil Annette H M, Knevel Rachel, van der Heijde Désirée, Huizinga Tom W J
Abstract excerpt
Joint destruction is a measure for RA severity that is accurate, sensitive and reflective of the cumulative disease burden. Risk factors for this outcome measure may be used to arrive at individualized treatment strategies. Currently, relatively few risk factors for joint destruction are known. New risk factors, genetic risk factors in particular, may have relatively small effects on the rate of joint...
Topics
- Arthritis, Rheumatoid
- Arthrography
- Disease Progression
- Genetic Predisposition to Disease
- Humans
- Joints
- Phenotype
- Predictive Value of Tests
- Range of Motion, Articular
- Reference Values