Article
Osteocalcin gene polymorphisms influence concentration of serum osteocalcin and enhance fracture identification.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2010
McGuigan Fiona, Kumar Jitender, Ivaska Kaisa K, Obrant Karl J, Gerdhem Paul, Akesson Kristina
Abstract excerpt
Osteoporosis is a major health problem affecting more than 75 million people throughout Europe, the United States, and Japan. Epidemiologic studies have determined that both genetic and environmental factors contribute to the pathogenesis of osteoporosis. We have investigated the association between polymorphisms at the osteocalcin locus and variables linked to bone health. Osteocalcin provides a link between...
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