Article
Fracture, bone mineral density, and the effects of calcitonin receptor gene in postmenopausal Koreans.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Aug 2010
Lee H-J, Kim S-Y, Kim G S, Hwang J-Y, Kim Y-J, Jeong B, Kim T-H, Park E K, Lee S H, Kim H-L, Koh J-M, Lee J-Y
Abstract excerpt
SUMMARY: In a candidate gene association study, we found that the variations of calcitonin receptor (CALCR) gene were related to the risk of vertebral fracture and increased bone mineral density (BMD). INTRODUCTION: Calcitonins through calcitonin receptors inhibit osteoclast-mediated bone resorption and modulate calcium ion excretion by the kidney and also prevent vertebral bone loss in early menopause. METHODS:...
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