Article
A segregation analysis of Barrett's esophagus and associated adenocarcinomas.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2010
Sun Xiangqing, Elston Robert, Barnholtz-Sloan Jill, Falk Gary, Grady William M, Kinnard Margaret, Mittal Sumeet K, Willis Joseph E, Markowitz Sanford, Brock Wendy, Chak Amitabh
Abstract excerpt
Familial aggregation of esophageal adenocarcinomas, esophagogastric junction adenocarcinomas, and their precursor Barrett's esophagus (BE) has been termed familial BE (FBE). Numerous studies documenting increased familial risk for these diseases raise the hypothesis that there may be an inherited susceptibility to the development of BE and its associated cancers. In this study, using segregation analysis for a...
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