Article
Segregation analysis of esophageal cancer in a moderately high-incidence area of northern China.
American journal of human genetics - 1 Jul 2000
Zhang W, Bailey-Wilson J E, Li W, Wang X, Zhang C, Mao X, Liu Z, Zhou C, Wu M
Abstract excerpt
In order to explore the mode of inheritance of esophageal cancer in a moderately high-incidence area of northern China, we conducted a pedigree survey on 225 patients affected by esophageal cancer in Yangquan, Shanxi Province. Segregation analysis was performed using the REGTL program of S.A.G.E. The results showed that Mendelian autosomal recessive inheritance of a major gene that influences susceptibility to...
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