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Article

Vitronectin binds to the head region of <i>Moraxella catarrhalis</i> ubiquitous surface protein A2 and confers complement‐inhibitory activity

19 Feb 2010

Abstract excerpt

The serum resistance of the common respiratory pathogen Moraxella catarrhalis is mainly dependent on ubiquitous surface proteins (Usp) A1 and A2 that interact with complement factor 3 (C3) and complement inhibitor C4b binding protein (C4BP) preventing the alternative and classical pathways of the complement system respectively. UspA2 also has the capacity to attract vitronectin that in turn binds C9 and hereby...

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PMID: 20199596
DOI: 10.1111/j.1365-2958.2010.07066.x

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Vitronectin binds to the head region of <i>Moraxella catarrhalis</i> ubiquitous surface protein A2 and confers complement‐inhibitory activityPMID 20199596Read ↗

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