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Article

Glycomic and transcriptomic response of GSC11 glioblastoma stem cells to STAT3 phosphorylation inhibition and serum-induced differentiation.

Journal of proteome research - 7 May 2010

He Huan, Nilsson Carol L, Emmett Mark R, Marshall Alan G, Kroes Roger A, Moskal Joseph R, Ji Yongjie, Colman Howard, Priebe Waldemar, Lang Frederick F, Conrad Charles A

Abstract excerpt

A glioblastoma stem cell (GSC) line, GSC11, grows as neurospheres in serum-free media supplemented with EGF (epidermal growth factor) and bFGF (basic fibroblast growth factor), and, if implanted in nude mice brains, will recapitulate high-grade glial tumors. Treatment with a STAT3 (signal transdu...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20199106
DOI: 10.1021/pr900793a

Genes

STAT3
GSC
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20199106-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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