Article
Engineered interfaces of an AAA+ ATPase reveal a new nucleotide-dependent coordination mechanism.
The Journal of biological chemistry - 14 May 2010
Joly Nicolas, Buck Martin
Abstract excerpt
Homohexameric ring AAA(+) ATPases are found in all kingdoms of life and are involved in all cellular processes. To accommodate the large spectrum of substrates, the conserved AAA(+) core has become specialized through the insertion of specific substrate-binding motifs. Given their critical roles...
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