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Article

Mechanism of homotropic control to coordinate hydrolysis in a hexameric AAA+ ring ATPase.

Journal of molecular biology - 1 Aug 2008

Schumacher Jörg, Joly Nicolas, Claeys-Bouuaert Inaki Leoz, Aziz Shaniza Abdul, Rappas Mathieu, Zhang Xiaodong, Buck Martin

Abstract excerpt

AAA(+) proteins are ubiquitous mechanochemical ATPases that use energy from ATP hydrolysis to remodel their versatile substrates. The AAA(+) characteristic hexameric ring assemblies raise important questions about if and how six often identical subunits coordinate hydrolysis and associated motion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18599077
DOI: 10.1016/j.jmb.2008.05.075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18599077-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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