Article
PARP-1 Val762Ala polymorphism is associated with reduced risk of non-Hodgkin lymphoma in Korean males.
BMC medical genetics - 3 Mar 2010
Jin Xue Mei, Kim Hee Nam, Lee Il-Kwon, Park Kyeong-Soo, Kim Hyeoung-Joon, Choi Jin-Su, Juhng Sang Woo, Choi Chan
Abstract excerpt
BACKGROUND: Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme that plays a role in DNA repair, differentiation, proliferation, and cell death. The polymorphisms of PARP-1 have been associated with the risk of various carcinomas, including breast, lung, and prostate. We investigated wheth...
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