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Article

Polymorphisms in IL-1beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis.

BMC medical genetics - 2 Mar 2010

Motsinger-Reif Alison A, Antas Paulo R Z, Oki Noffisat O, Levy Shawn, Holland Steven M, Sterling Timothy R

Abstract excerpt

BACKGROUND: Human genetic variants may affect tuberculosis susceptibility, but the immunologic correlates of the genetic variants identified are often unclear. METHODS: We conducted a pilot case-control study to identify genetic variants associated with extrapulmonary tuberculosis in patients with previously characterized immune defects: low CD4+ lymphocytes and low unstimulated cytokine production. Two genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20196868
DOI: 10.1186/1471-2350-11-37
PMCID: PMC2837863

Genes

VDR
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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