Article
Circulating nucleic acids as a potential source for cancer biomarkers.
Current molecular medicine - 1 Mar 2010
Vlassov V V, Laktionov P P, Rykova E Y
Abstract excerpt
Since the association of circulating DNA level changes with tumor growth was discovered many attempts have been made to develop the sensitive and robust blood-based tests for early tumor diagnostics. Both genomic as well as mitochondrial DNA quantification in the circulation have been extensively evaluated as a diagnostic and prognostic tool to monitor cancer therapy. Cell-free DNA bearing the same genetic and...
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