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Article

Cell-free nucleic acids as biomarkers in cancer patients.

Nature reviews. Cancer - 1 Jun 2011

Schwarzenbach Heidi, Hoon Dave S B, Pantel Klaus

Abstract excerpt

DNA, mRNA and microRNA are released and circulate in the blood of cancer patients. Changes in the levels of circulating nucleic acids have been associated with tumour burden and malignant progression. In the past decade a wealth of information indicating the potential use of circulating nucleic acids for cancer screening, prognosis and monitoring of the efficacy of anticancer therapies has emerged. In this...

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PMID: 21562580
DOI: 10.1038/nrc3066

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