Article
Circulating nucleic acids as a tumor marker.
Histology and histopathology - 1 Jan 2002
Chan K C A, Lo Y M D
Abstract excerpt
Patients suffering from malignant diseases have been shown to have increased amounts of cell free nucleic acids in their circulation. As genetic and epigenetic alterations are increasingly characterized in different types of tumors, such changes can be used to detect tumor-derived nucleic acids in the circulation. To date, nearly all tumor-associated nucleic acids have been detected in the plasma or serum of...
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