Article
An atypical riboflavin pathway is essential for Brucella abortus virulence.
PloS one - 25 Feb 2010
Bonomi Hernán Ruy, Marchesini María Inés, Klinke Sebastián, Ugalde Juan E, Zylberman Vanesa, Ugalde Rodolfo A, Comerci Diego J, Goldbaum Fernando Alberto
Abstract excerpt
Brucellosis is a worldwide zoonosis that affects livestock and humans and is caused by closely related Brucella spp., which are adapted to intracellular life within cells of a large variety of mammals. Brucella can be considered a furtive pathogen that infects professional and non-professional phagocytes. In these cells Brucella survives in a replicative niche, which is characterized for having a very low oxygen...
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