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Riboflavin Analogs as Antiinfectives: Occurrence, Mode of Action, Metabolism and Resistance

1 Mar 2013

Abstract excerpt

Antimetabolites are molecules, which are structurally similar to molecules needed to carry out primary metabolic reactions.The inhibitory activity of an antimetabolite depends on its successful competition with the natural substrate, ligand, modulator or cofactor of a given biomolecule. Antimetabolites are indispensable as molecular tools in order to understand biological processes. Beyond that,antimetabolites...

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PMID: 23116394
DOI: 10.2174/1381612811319140006

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