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Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays

22 Oct 2007

Abstract excerpt

Ovarian cancer is a leading cause of deaths, yet many aspects of the biology of the disease and a routine means of its detection are lacking. We have used protein microarrays and autoantibodies from cancer patients to identify proteins that are aberrantly expressed in ovarian tissue. Sera from 30 cancer patients and 30 healthy individuals were used to probe microarrays containing 5,005 human proteins. Ninety-four...

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PMID: 17954908
DOI: 10.1073/pnas.0708572104

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