Decreased in vitro susceptibility of Plasmodium falciparum isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001 to 2007.

doi:10.1128/AAC.01304-09

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Decreased in vitro susceptibility of Plasmodium falciparum isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001 to 2007.

Antimicrobial agents and chemotherapy - 1 May 2010

Lim Pharath, Wongsrichanalai Chansuda, Chim Pheaktra, Khim Nimol, Kim Saorin, Chy Sophy, Sem Rithy, Nhem Sina, Yi Poravuth, Duong Socheat, Bouth Denis Mey, Genton Blaise, Beck Hans-Peter, Gobert Jean Gerard, Rogers William O, Coppee Jean-Yves, Fandeur Thierry, Mercereau-Puijalon Odile, Ringwald Pascal, Le Bras Jacques, Ariey Frederic

Abstract excerpt

This study describes the results of in vitro antimalarial susceptibility assays and molecular polymorphisms of Plasmodium falciparum isolates from Cambodia. The samples were collected from patients enrolled in therapeutic efficacy studies (TES) conducted by the Cambodian National Malaria Control Program for the routine efficacy monitoring of artemisinin-based combination therapy (ACT) (artesunate-mefloquine and...

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PMID: 20194689
DOI: 10.1128/AAC.01304-09
PMCID: PMC2863643

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