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Article

Successful treatment of steroid-resistant nephrotic syndrome associated with WT1 mutations.

Pediatric nephrology (Berlin, Germany) - 1 Jul 2010

Gellermann Jutta, Stefanidis Constantinos J, Mitsioni Andromachi, Querfeld Uwe

Abstract excerpt

The Wilms' tumor suppressor gene 1 (WT1) encodes a transcription factor involved in kidney and gonadal development. WT1 is also a key regulator of podocyte functions and mutations have been found in a small percentage of children with isolated or syndromal steroid-resistant nephrotic syndrome. It is commonly assumed that the nephrotic syndrome (NS) in patients with WT1 mutations is unresponsive to therapy and...

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Identifiers

PMID: 20191369
DOI: 10.1007/s00467-010-1468-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Successful treatment of steroid-resistant nephrotic syndrome associated with WT1 mutations.PMID 20191369Read ↗

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Membranoproliferative glomerulonephritis associated with a mutation in Wilms' tumour suppressor gene 1.Semantic proximity Read ↗

Spectrum of early onset nephrotic syndrome associated with WT1 missense mutations.Semantic proximity Read ↗

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