Article
WT1 mutation-associated nephropathy: a single-center experience .
Clinical nephrology - 1 May 2017
Yue Zhihui, Wang Haiyan, Lin Hongrong, Yang Juan, Liu Ting, Liu Yulin, Chen Huamu, Sun Liangzhong
Abstract excerpt
This study explored Wilms' tumor 1 (WT1) mutations in children with, or suspected of having, steroid-resistant nephrotic syndrome (SRNS), referred to or treated in our hospital in the past 6 years as well as the correlation between genotype and phenotype in WT1 mutation-associated nephropathy in Chinese patients. In total, 76 patients participated in the study. WT1 mutations were identified in 15 patients, 5 of...
Topics
- Adolescent
- Child
- Child, Preschool
- Codon, Nonsense
- Female
- Genotype
- Humans
- Infant
- Male
- Mutation
- Mutation, Missense
- Nephrotic Syndrome
- WT1 Proteins