Article
Wilms' tumour 1 gene mutations in south Indian children with steroid-resistant nephrotic syndrome.
The Indian journal of medical research - 1 Aug 2016
Kumar Aravind Selvin, Srilakshmi R, Karthickeyan Smk, Balakrishnan K, Padmaraj R, Senguttuvan Prabha
Abstract excerpt
BACKGROUND & OBJECTIVES: Clinically, nephrotic syndrome (NS) is a diverse group of symptoms; about 20 per cent of NS cases are resistant to steroid treatment, and within ten years they progress to end-stage renal disease. The present study was undertaken to identify the mutations of Wilms' tumour 1 (WT1) gene in steroid-resistant NS (SRNS) children. METHODS: A total of 173 children with SRNS and 100 children in...
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