Article
Arabidopsis RNA-dependent RNA polymerases and dicer-like proteins in antiviral defense and small interfering RNA biogenesis during Turnip Mosaic Virus infection.
The Plant cell - 1 Feb 2010
Garcia-Ruiz Hernan, Takeda Atsushi, Chapman Elisabeth J, Sullivan Christopher M, Fahlgren Noah, Brempelis Katherine J, Carrington James C
Abstract excerpt
Plants respond to virus infections by activation of RNA-based silencing, which limits infection at both the single-cell and system levels. Viruses encode RNA silencing suppressor proteins that interfere with this response. Wild-type Arabidopsis thaliana is immune to silencing suppressor (HC-Pro)-deficient Turnip mosaic virus, but immunity was lost in the absence of DICER-LIKE proteins DCL4 and DCL2. Systematic...
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