Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dietary α‐tocopherol and neuromuscular health: Search for optimal dose and molecular mechanisms continues!

25 Feb 2010

Abstract excerpt

Rodents fed alpha-tocopherol (alphaT)-depleted diets develop neuromuscular deficits. Unequivocal role of alphaT in the prevention of these deficits is confounded by possible neurotoxic oxidant products generated, ex vivo in alphaT-depleted diets. The discovery that large doses of alphaT could ameliorate neuromuscular deficits, attributed to very low serum alphaT caused by mutations in either the microsomal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidant Activity and Oxidative Stress
Share to Coenzyme Q10 studies and effects

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20187127
DOI: 10.1002/mnfr.200900575

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dietary α‐tocopherol and neuromuscular health: Search for optimal dose and molecular mechanisms continues!PMID 20187127Read ↗

Delayed-onset ataxia in mice lacking alpha -tocopherol transfer protein: model for neuronal degeneration caused by chronic oxidative stress.Semantic proximity Read ↗

Alpha-tocopherol transfer protein deficiency in mice causes multi-organ deregulation of gene networks and behavioral deficits with age.Semantic proximity Read ↗

Vitamin E and Phosphoinositides Regulate the Intracellular Localization of the Hepatic α-Tocopherol Transfer Protein.Semantic proximity Read ↗

Biochemical consequences of heritable mutations in the alpha-tocopherol transfer protein.Semantic proximity Read ↗

PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic DiseasesSemantic proximity Read ↗

Molecular mechanisms of vitamin E transport.Semantic proximity Read ↗

α-Tocopherol Transfer Protein Is Important for the Normal Development of Placental Labyrinthine Trophoblasts in MiceSemantic proximity Read ↗

Prevention of Mutation, Cancer, and Other Age‐Associated Diseases by Optimizing Micronutrient IntakeSemantic proximity Read ↗

Thyroid Hormone Receptor α Regulates Autophagy, Mitochondrial Biogenesis, and Fatty Acid Use in Skeletal Muscle.Semantic proximity Read ↗

Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.Semantic proximity Read ↗

Mitochondrial trifunctional protein defects: clinical implications and therapeutic approaches.Semantic proximity Read ↗

Synthetic α-Tocopherol, Compared with Natural α-Tocopherol, Downregulates Myelin Genes in Cerebella of Adolescent Ttpa-null MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.