Article
Injury of rat pulmonary alveolar epithelial cells by H2O2: dependence on phenotype and catalase.
The American journal of physiology - 1 Apr 1991
Simon R H, Edwards J A, Reza M M, Kunkel R G
Abstract excerpt
In a variety of inflammatory lung diseases, type I alveolar epithelial cells are more likely to be injured than are type II cells. Because oxidants have been implicated as a cause of injury in various inflammatory lung diseases, we evaluated the effects of differentiation on alveolar epithelial cell susceptibility to H2O2-induced injury. With the use of isolated rat type II cells in culture, we found that the...
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