Article
Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool
22 Feb 2010
Abstract excerpt
Short telomeres of circulating leukocytes are a risk factor for age-related diseases, such as atherosclerosis, but the exact mechanisms generating variations in telomere length are unknown. We hypothesized that induction of differentiated T cells during chronic CMV infection would affect T cell telomere length. To test this, we measured the amount of differentiated T cells and telomere length of lymphocytes...
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