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Article

The human G93A SOD1 phenotype closely resembles sporadic amyotrophic lateral sclerosis.

Journal of neurology, neurosurgery, and psychiatry - 1 Jul 2010

Synofzik Matthis, Fernández-Santiago Rubén, Maetzler Walter, Schöls Ludger, Andersen Peter M

Abstract excerpt

Transgenic mouse models of human SOD1 mutations have opened up an area of intense investigation into the pathogenesis of familial and sporadic amyotrophic lateral sclerosis (ALS). However, the human phenotype of the G93A SOD1 mutation-the most commonly studied mutation in rodent models-has remain...

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Identifiers

PMID: 20176600
DOI: 10.1136/jnnp.2009.181719

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20176600-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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