Article
Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes.
Inorganic chemistry - 15 Mar 2010
Hadler Kieran S, Mitić Natasa, Yip Sylvia Hsu-Chen, Gahan Lawrence R, Ollis David L, Schenk Gerhard, Larrabee James A
Abstract excerpt
The glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes is a promiscuous, dinuclear metallohydrolase that has potential application in the remediation of organophosphate nerve agents and pesticides. GpdQ employs an unusual reaction mechanism in which the enzyme is predominantly mononuclea...
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