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Article

Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization.

Cell cycle (Georgetown, Tex.) - 1 Mar 2010

Bashir Tarig, Pagan Julia K, Busino Luca, Pagano Michele

Abstract excerpt

F-box proteins are the substrate recognition subunits of SCF (Skp1, Cul1, F-box protein) ubiquitin ligase complexes. Skp2 is a nuclear F-box protein that targets the CDK inhibitor p27 for ubiquitin- and proteasome-dependent degradation. In G(0) and during the G(1) phase of the cell cycle, Skp2 is...

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Share to Anaphase-Promoting Complex-Cyclosome
Share to Cullin Proteins
Share to Cyclin-Dependent Kinase Inhibitor p27

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Resting Phase, Cell Cycle

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Source

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Identifiers

PMID: 20160477
DOI: 10.4161/cc.9.5.10914
PMCID: PMC3827631

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20160477-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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