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Article

Chromatin modifications: The driving force of senescence and aging?

13 Feb 2009

Abstract excerpt

An emerging field of investigation in the search for treatment of human disease is the modulation of chromatin modifications. Chromatin modifications impart virtually all processes occurring in the mammalian nucleus, from regulation of transcription to genomic stability and nuclear high order organization. It has been well recognized that, as the mammalian cell ages, its chromatin structure evolves, both at a...

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Share to Epigenetics and DNA Methylation
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PMID: 20157508
DOI: 10.18632/aging.100023

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