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Article

Genetic susceptibility, smoking, obesity and risk of venous thromboembolism.

British journal of haematology - 1 Apr 2010

Severinsen Marianne T, Overvad Kim, Johnsen Søren P, Dethlefsen Claus, Madsen Poul H, Tjønneland Anne, Kristensen Søren R

Abstract excerpt

The F5 G1691A (Factor V Leiden) and F2 G20210A (prothrombin) mutations are linked to an increase in the incidence rate of venous thromboembolism (VTE), but their effects are highly variable. We investigated whether the effects of smoking and obesity might explain this variability. In a case-cohort study including the participants of the Danish Diet, Cancer and Health study, we computed incidence rates and Cox...

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PMID: 20148880
DOI: 10.1111/j.1365-2141.2010.08086.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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