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Article

MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1.

PloS one - 4 Feb 2010

Busch Courtney R, DiRuggiero Jocelyne

Abstract excerpt

BACKGROUND: The genome of the halophilic archaeon Halobacterium salinarum NRC-1 encodes for homologs of MutS and MutL, which are key proteins of a DNA mismatch repair pathway conserved in Bacteria and Eukarya. Mismatch repair is essential for retaining the fidelity of genetic information and defects in this pathway result in the deleterious accumulation of mutations and in hereditary diseases in humans....

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Identifiers

PMID: 20140215
DOI: 10.1371/journal.pone.0009045
PMCID: PMC2816208

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Source receipt: pubmed, retrieved 7 Sept 2026.

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MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1.PMID 20140215Read ↗

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