Article
Both homo and heterodimers of Marek's disease virus encoded Meq protein contribute to transformation of lymphocytes in chickens.
Virology - 10 Apr 2010
Suchodolski Paulette F, Izumiya Yoshihiro, Lupiani Blanca, Ajithdoss Dharani K, Lee Lucy F, Kung Hsing-Jien, Reddy Sanjay M
Abstract excerpt
Marek' disease virus serotype-1, also know as Gallid herpesvirus 2 (GaHV-2), elicits T-cell lymphomas in chickens. The GaHV-2 genome encodes an oncoprotein, Meq, with similarity to the Jun/Fos family of proteins. We have previously shown that Meq homodimers are not sufficient to induce lymphomas...
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