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Article

Folate-mediated one-carbon metabolism and its effect on female fertility and pregnancy viability.

Nutrition reviews - 1 Feb 2010

Laanpere Margit, Altmäe Signe, Stavreus-Evers Anneli, Nilsson Torbjörn K, Yngve Agneta, Salumets Andres

Abstract excerpt

This review summarizes current knowledge of the effect of folate-mediated one-carbon metabolism and related genetic variants on female fertility and pregnancy viability. Insufficient folate status disrupts DNA methylation and integrity and increases blood homocysteine levels. Elevated levels of f...

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Source

Identifiers

PMID: 20137055
DOI: 10.1111/j.1753-4887.2009.00266.x

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20137055-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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