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Article

Impact of folate and homocysteine metabolism on human reproductive health

16 Feb 2007

Abstract excerpt

Folates belong to the vitamin B group and are involved in a large number of biochemical processes, particularly in the metabolism of homocysteine. Dietary or genetically determined folate deficiency leads to mild hyperhomocysteinemia, which has been associated with various pathologies. Molecular mechanisms of homocysteine-induced cellular dysfunction include increased inflammatory cytokine expression, altered...

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PMID: 17307774
DOI: 10.1093/humupd/dml063

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