Article
Familial chronic lymphocytic leukemia in Norway and Denmark. Comments on pleiotropy and birth order.
In vivo (Athens, Greece) - 1 Jan 2000
Jønsson Viggo, Tjønnfjord Geir E, Johannesen Tom B, Ly Bernt, Olsen Jørgen H, Yuille Martin
Abstract excerpt
AIM: To investigate the genetics of chronic lymphocytic leukemia (CLL). MATERIALS AND METHODS: In 56 (7%) out of 800 CLL patients with concomitant malignant hematological disease, 51 families and 141 cases were ascertained. RESULT: 106 cases (75%) of CLL, 27 cases (19%) of nonCLL and 8 cases (6%) of myeloproliferative disorders. Paternal disease was transmitted primarily to the youngest sons in the sibship while...
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