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Article

Prague hereditary hypercholesterolemic (PHHC) rat - a model of polygenic hypercholesterolemia.

Physiological research - 1 Jan 2009

Kovář J, Tonar Z, Heczková M, Poledne R

Abstract excerpt

Prague hereditary hypercholesterolemic (PHHC) rat - rat strain crossbred from Wistar rats - is a model of hypercholesterolemia induced by dietary cholesterol. Importantly, no bile salts and/or antithyroid drugs need to be added to the diet together with cholesterol to induce hypercholesterolemia. PHHC rats have only modestly increased cholesterolemia when fed a standard chow and develop hypercholesterolemia...

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Source

Identifiers

PMID: 20131941
DOI: 10.33549/physiolres.931916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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