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Article

Nucleotide-binding oligomerization domain 2 and Toll-like receptor 2 function independently in a murine model of arthritis triggered by intraarticular peptidoglycan.

Arthritis and rheumatism - 1 Apr 2010

Rosenzweig Holly L, Jann Monica J, Vance Emily E, Planck Stephen R, Rosenbaum James T, Davey Michael P

Abstract excerpt

OBJECTIVE: Blau syndrome is an autoinflammatory disease resulting from mutations in the NOD2 gene, wherein granulomatous arthritis, uveitis, and dermatitis develop. The mechanisms by which aberrant NOD2 causes joint inflammation are poorly understood. Indeed, very few studies have addressed the f...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Nod2 Signaling Adaptor Protein

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Source

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Identifiers

PMID: 20131263
DOI: 10.1002/art.27335
PMCID: PMC2945367

Genes

CSK
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20131263-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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