Article
From monogenic to polygenic obesity: recent advances.
European child & adolescent psychiatry - 1 Mar 2010
Hinney Anke, Vogel Carla I G, Hebebrand Johannes
Abstract excerpt
The heritability of obesity and body weight in general is high. A small number of confirmed monogenic forms of obesity-the respective mutations are sufficient by themselves to cause the condition in food abundant societies-have been identified by molecular genetic studies. The elucidation of these genes, mostly based on animal and family studies, has led to the identification of important pathways to the disorder...
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