Article
The predictive value of genetic variations in the vascular endothelial growth factor A gene in metastatic colorectal cancer.
The pharmacogenomics journal - 1 Feb 2011
Hansen T F, Garm Spindler K-L, Andersen R F, Lindebjerg J, Brandslund I, Jakobsen A
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) in the vascular endothelial growth factor A (VEGF-A) gene may have clinical implications. The aim of this study was to investigate the possible predictive value of the VEGF-A SNPs, in patients with metastatic colorectal cancer (mCRC) treated with first-line capecitabine and oxaliplatin (XELOX). The study included 72 patients with mCRC. Genomic DNA was isolated from whole...
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