Article
Using response to a standardized treatment to identify phenotypes for genetic studies of chronic rhinosinusitis.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale - 1 Feb 2010
Nader Marc-Elie, Abou-Jaoude Peter, Cabaluna Myrna, Desrosiers Martin
Abstract excerpt
OBJECTIVES: Studies of the genetics of chronic rhinosinusitis offer potential insights into the pathophysiology of this poorly understood condition. However, genetic studies are both expensive and time consuming-hence the importance of establishing beforehand the proper population and target genes. We wished to identify patient factors associated with a proposed definition of severe chronic rhinosinusitis to...
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