Using response to a standardized treatment to identify phenotypes for genetic studies of chronic rhinosinusitis.

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Article

Using response to a standardized treatment to identify phenotypes for genetic studies of chronic rhinosinusitis.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale - 1 Feb 2010

Nader Marc-Elie, Abou-Jaoude Peter, Cabaluna Myrna, Desrosiers Martin

Abstract excerpt

OBJECTIVES: Studies of the genetics of chronic rhinosinusitis offer potential insights into the pathophysiology of this poorly understood condition. However, genetic studies are both expensive and time consuming-hence the importance of establishing beforehand the proper population and target genes. We wished to identify patient factors associated with a proposed definition of severe chronic rhinosinusitis to...

Topics

Administration, Intranasal
Anti-Inflammatory Agents
Bacterial Infections
Budesonide
Chronic Disease
Dermatitis, Atopic
Female
Genetic Techniques
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Phenotype

Retrospective Studies

Rhinitis

Sinusitis

Therapeutic Irrigation

Source

Open in PubMed

Identifiers

PMID: 20122348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20122348-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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